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Molecular testing and advanced diagnostics

The 42 companies in this industry listed on the NYSE and Nasdaq are worth $131 bn combined; the largest are Natera (NTRA), Guardant Health (GH) and Tempus AI, Inc. (TEM). For each one: what it does, revenue, margin, free cash flow over the last five years and a score from 0 to 10.

Data as of October 2026

Comfortable leader
42 companies value 131 bn revenue 14 bn margin -20.6% free cash flow -1.1 bn avg. score 0.9
NTRA holds 44.0% of the group's value, 2.7x the runner-up
Rank Ticker Company Share Value Revenue Margin FCF 5 years FCF/px Yield What it does · why it is here
1 NTRA Natera
United States · score 2.6
44% 58 bn 2.7 bn -7.1% 0.1 bn 0.1% — Genetic testing for prenatal care, cancer and transplants · Leader in DNA testing for pregnancy, oncology and transplants
2 GH Guardant Health
United States · score 0.0
16% 21 bn 1.2 bn -38.3% -0.2 bn -1.1% — Blood tests for precision oncology · Liquid biopsy for oncology: detects cancer with a blood test
3 TEM Tempus AI, Inc.
United States · score 0.0
9% 12 bn 1.4 bn -17.8% -0.3 bn -2.3% — Intelligent testing linking lab results to clinical data · Illinois — revenue of $1.4bn
4 CAI Caris Life Sciences, Inc.
United States · score 4.9
7% 8.7 bn 1.0 bn 10.6% 0.1 bn 1.7% — AI-driven drug discovery and precision medicine · Texas — revenue of $990m
5 GRAL GRAIL, Inc.
United States · score 0.0
4% 5.5 bn 0.2 bn -236.9% -0.3 bn -5.4% — Early cancer detection at population scale · California — revenue of $165m
6 BLLN BillionToOne, Inc.
United States · score 4.7
4% 4.8 bn 0.4 bn 9.5% 0.0 bn 0.7% — Non-invasive liquid biopsy with sequencing and AI · California — revenue of $397m
7 ADPT Adaptive Biotechnologies Corp
United States · score 0.3
3% 3.8 bn 0.3 bn -20.7% -0.0 bn -0.6% — Immune system sequencing for diagnostics and research · Washington — revenue of $308m
8 VCYT VERACYTE, INC.
United States · score 5.7
3% 3.5 bn 0.6 bn 20.4% 0.2 bn 4.7% — Genomic tests for cancer diagnosis · California — revenue of $562m
9 CDNA CareDx, Inc.
United States · score 5.2
3% 3.5 bn 0.5 bn 24.2% 0.1 bn 2.7% — Precision medicine for transplant patients · California — revenue of $458m
10 NEO NEOGENOMICS INC
United States · score 0.4
2% 2.1 bn 0.8 bn -6.8% -0.0 bn -0.3% — Network of cancer testing labs in the US and the UK · Florida — revenue of $766m
11 WGS GeneDx Holdings Corp.
United States · score 0.0
2% 2.0 bn 0.5 bn -23.4% -0.1 bn -3.8% — Exome and genome testing for clinical diagnosis · Connecticut — revenue of $454m
12 PSNL Personalis, Inc.
United States · score 0.0
1% 1.7 bn 0.1 bn -153.8% -0.1 bn -6.0% — Advanced cancer genomic testing · California — revenue of $70m
13 CSTL CASTLE BIOSCIENCES INC
United States · score 1.0
1% 1.0 bn 0.4 bn -5.4% 0.0 bn 0.0% — Molecular diagnostics for skin cancers and other diseases · Texas — revenue of $357m
14 QDEL QuidelOrtho Corp
United States · score 0.0
1% 0.9 bn 2.7 bn -39.2% -0.2 bn -24.1% — Diagnostics with factories in the US, UK and China · California — revenue of $2.7bn
15 FLGT Fulgent Genetics, Inc.
United States · score 0.3
0% 0.6 bn 0.3 bn -26.0% -0.1 bn -18.8% — Lab services and therapeutic development · California — revenue of $324m
16 NNNN Anbio Biotechnology
Germany · score 3.0
0% 0.5 bn 0.0 bn 74.0% -0.0 bn -1.4% — Rapid diagnostic tests, with operations in Europe · Germany — revenue of $9m
17 MYGN MYRIAD GENETICS INC
United States · score 2.2
0% 0.4 bn 0.8 bn -14.0% 0.0 bn 1.9% — Molecular and genetic tests for patients and doctors · Utah — revenue of $807m
18 YDES YD Bio Ltd
Taiwan · score 2.0
0% 0.4 bn 0.0 bn 24.7% -0.0 bn -2.0% — Diagnostics and health products · Taiwan — revenue of $1m
19 OSUR ORASURE TECHNOLOGIES INC
United States · score 0.0
0% 0.3 bn 0.1 bn -43.7% -0.1 bn -18.9% — Rapid HIV, hepatitis C and covid tests, including at-home tests · Pennsylvania — revenue of $112m
20 BDSX BIODESIX INC
United States · score 0.0
0% 0.2 bn 0.1 bn -27.0% -0.0 bn -8.2% — Diagnostics, with a focus on lung solutions · Colorado — revenue of $103m
21 XGN EXAGEN INC.
United States · score 0.0
0% 0.2 bn 0.1 bn -26.6% -0.0 bn -4.2% — AVISE tests for diagnosing rheumatic and autoimmune diseases · California — revenue of $71m
22 BNR Burning Rock Biotech Ltd
China · score 0.4
0% 0.1 bn 0.1 bn -10.3% 0.0 bn -3.6% — Genomic cancer diagnostics in China · China — revenue of $77m
23 LUCD Lucid Diagnostics Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn -959.8% -0.1 bn -61.6% — Tests for early detection of esophageal cancer · New York — revenue of $5m
24 IMDX Insight Molecular Diagnostics Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn -30x -0.0 bn -32.8% — Molecular diagnostic kits for use in the lab itself · Tennessee — revenue of $2m
25 SERA SERA PROGNOSTICS, INC.
United States · score 0.0
0% 0.1 bn 0.0 bn -475x -0.0 bn -35.1% — Proteomic tests for maternal and neonatal health · Utah
26 MDXH MDxHealth SA
Belgium · score 0.0
0% 0.0 bn 0.1 bn -31.1% 0.0 bn -19.1% — Molecular prostate cancer tests (Confirm mdx, GPS mdx, Exo mdx) for urologists in the US · Belgium — revenue of $108m
27 TRIB TRINITY BIOTECH PLC
Ireland · score 0.0
0% 0.0 bn 0.0 bn -82.0% -0.0 bn -89.8% — Human diagnostics and biosensors for diabetes, from Ireland · Ireland — revenue of $44m
28 PRPO Precipio, Inc.
United States · score 2.6
0% 0.0 bn 0.0 bn -4.5% 0.0 bn 2.0% — Diagnostic biotech for blood cancers · Connecticut — revenue of $27m
29 BIAF bioAffinity Technologies, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -257.3% -0.0 bn -256.9% — Noninvasive AI-powered lung cancer diagnostics · Texas — revenue of $6m
30 CNSY CERENOME, INC.
United States · score 0.0
0% 0.0 bn 0.0 bn -620.7% -0.0 bn -188.4% — Cerebrospinal fluid tests for central nervous system cancers and a radiopharmaceutical in development · Texas — revenue of $4m
31 BMRA BIOMERICA INC
United States · score 0.0
0% 0.0 bn 0.0 bn -115.5% 0.0 bn -48.8% — Patented diagnostic and therapeutic products · California — revenue of $4m
32 ACON Aclarion, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -109x -0.0 bn -150.2% — Magnetic resonance spectroscopy technology · Colorado
33 VNRX VOLITIONRX LTD
United States · score 0.0
0% 0.0 bn 0.0 bn — -0.0 bn -384.0% — Epigenetic blood tests for human and veterinary cancer · Nevada — revenue of $2m
34 CDIO Cardio Diagnostics Holdings, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -462x -0.0 bn -118.9% — Epigenetics-based clinical tests for cardiovascular disease · Illinois
35 INBS INTELLIGENT BIO SOLUTIONS INC.
United States · score 0.0
0% 0.0 bn 0.0 bn -294.9% -0.0 bn -262.0% — Medical technology for rapid, noninvasive testing · New York — revenue of $4m
36 AIDX 20/20 Biolabs, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -285.0% 0.0 bn -84.6% — AI blood tests for early cancer detection · Maryland — revenue of $2m
37 VRAX Virax Biolabs Group Ltd
United Kingdom · score 0.0
0% 0.0 bn 0.0 bn -419x 0.0 bn -256.7% — Infectious disease and immunology diagnostics · United Kingdom
38 BJDX Bluejay Diagnostics, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -196.0% — Critical care diagnostics with a focus on sepsis · Massachusetts
39 NIKI Niki BioSolutions, Inc.
United Kingdom · score 0.0
0% 0.0 bn — — 0.0 bn -108.1% — MicroRNA blood tests for Alzheimer's, successor to a clinical-stage biopharmaceutical company · United Kingdom
40 ONCO Onconetix, Inc.
United States · score 0.5
— — 0.0 bn -16x -0.0 bn — — Proclarix blood test for prostate cancer diagnosis · Ohio
41 AIMD Ainos, Inc.
United States · score 0.1
— — 0.0 bn -1033x 0.0 bn — — Artificial olfaction technology and immunotherapy, from 1984 · Texas
42 FRNM Freenome, Inc.
United States · score 0.9
— — — — 0.0 bn — — — Blood tests for early cancer detection · California

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What this is. A catalogue, not a guide. Every industry with stocks listed on the NYSE or NASDAQ, the companies contending for its leadership, what each one does according to its own annual report, and the balance sheet it filed with the SEC.

The score runs from 0 to 10 and compares each company with every other one in the almanac on cash generation, profitability, debt, dividends and consistency over the last five years. The higher it is, the better the company fares in that comparison. Curious how much each part weighs? Ask at the bottom of the page.

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