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Clinical-stage pharmaceuticals

The 251 companies in this industry listed on the NYSE and Nasdaq are worth $203 bn combined; the largest are Revolution Medicines, Inc. (RVMD), Roivant Sciences Ltd. (ROIV) and Praxis Precision Medicines, Inc. (PRAX). For each one: what it does, revenue, margin, free cash flow over the last five years and a score from 0 to 10.

Data as of October 2026

Evenly matched
251 companies value 203 bn revenue 1.5 bn margin -342.7% free cash flow -19 bn avg. score 0.4
RVMD holds 19.2% of the group's value, 1.6x the runner-up
Rank Ticker Company Share Value Revenue Margin FCF 5 years FCF/px Yield What it does · why it is here
1 RVMD Revolution Medicines, Inc.
United States · score 0.0
19% 39 bn 0.0 bn — -1.2 bn -3.2% — Precision oncology for RAS-addicted cancers · California
2 ROIV Roivant Sciences Ltd.
United Kingdom · score 0.0
12% 25 bn 0.0 bn -35x -0.8 bn -3.3% — Biopharma accelerating drug development · United Kingdom — revenue of $8m
3 PRAX Praxis Precision Medicines, Inc.
United States · score 0.0
4% 7.3 bn 0.0 bn — -0.3 bn -4.2% — Precision neuroscience biopharma for CNS disorders · Massachusetts
4 ABVX Abivax S.A.
France · score 0.0
3% 6.9 bn 0.0 bn -80x -0.2 bn -3.2% — Therapies for chronic inflammatory diseases, from France · France — revenue of $6m
5 BLTE BELITE BIO, INC
United States · score 0.3
3% 5.8 bn — — -0.0 bn -0.6% — Therapies for retinal diseases · California
6 COGT Cogent Biosciences, Inc.
United States · score 0.0
3% 5.2 bn — — -0.3 bn -5.9% — Clinical-stage biotech in precision therapies · Massachusetts
7 MANE Veradermics, Inc
United States · score 0.7
3% 5.1 bn — — -0.1 bn -1.5% — Clinical-stage biopharma for dermatology and aesthetics · Connecticut
8 RGC Regencell Bioscience Holdings Ltd
Hong Kong · score 0.2
3% 5.0 bn — — -0.0 bn -0.2% — Traditional Chinese medicine bioscience for ADHD and autism · Hong Kong
9 ERAS Erasca, Inc.
United States · score 0.0
2% 4.8 bn — — -0.1 bn -2.1% — Clinical-stage precision oncology for RAS/MAPK pathway cancers · California
10 DFTX Definium Therapeutics, Inc.
United States · score 0.2
2% 4.4 bn — — -0.2 bn -3.8% — Clinical-stage biopharma for brain health disorders · New York
11 EWTX Edgewise Therapeutics, Inc.
United States · score 0.0
2% 4.1 bn — — -0.2 bn -3.9% — Sarcomere modulators for muscle diseases · Colorado
12 RLAY Relay Therapeutics, Inc.
United States · score 0.0
2% 3.7 bn 0.0 bn -28x -0.2 bn -5.7% — Small-molecule precision medicine for cancer · Massachusetts — revenue of $10m
13 AMLX Amylyx Pharmaceuticals, Inc.
United States · score 0.1
2% 3.4 bn 0.0 bn — -0.1 bn -3.7% — Clinical-stage pharma in therapies for unmet needs · Massachusetts
14 XENE Xenon Pharmaceuticals Inc.
Canada · score 0.0
2% 3.4 bn 0.0 bn — -0.3 bn -10.0% — Neuroscience biopharma · Canada
15 PBLS Parabilis Medicines, Inc.
United States · score 5.3
2% 3.1 bn — — — — — — Medicines for protein targets considered undruggable · Massachusetts
16 IRON Disc Medicine, Inc.
United States · score 0.0
2% 3.0 bn — — -0.2 bn -6.5% — Clinical-stage biopharma in serious blood diseases · Massachusetts
17 VKTX Viking Therapeutics, Inc.
United States · score 0.0
1% 2.9 bn 0.0 bn — -0.4 bn -14.3% — Therapies for metabolic and endocrine disorders · California
18 ELVN Enliven Therapeutics, Inc.
United States · score 0.2
1% 2.8 bn — — -0.1 bn -2.4% — Clinical-stage biopharma of small molecules · California
19 NRIX Nurix Therapeutics, Inc.
United States · score 6.5
1% 2.7 bn 0.7 bn 42.0% 0.4 bn 13.6% — Clinical-stage biopharma in targeted protein degradation · California — revenue of $702m
20 MBX MBX Biosciences, Inc.
United States · score 0.0
1% 2.5 bn — — -0.1 bn -3.4% — Clinical-stage biopharma in peptides for endocrine disorders · Indiana
21 NAMS NewAmsterdam Pharma Co N.V.
Netherlands · score 0.0
1% 2.4 bn 0.0 bn -36x -0.1 bn -5.9% — Late-stage biopharma in cardiometabolic diseases · Netherlands — revenue of $7m
22 SLS SELLAS Life Sciences Group, Inc.
United States · score 0.2
1% 2.1 bn — — -0.0 bn -1.3% — Clinical-stage biopharma of cancer therapies · New York
23 IMNM Immunome Inc.
United States · score 0.0
1% 1.9 bn 0.0 bn — -0.2 bn -11.5% — Biotech developing targeted oncology therapies · Washington
24 PHVS Pharvaris N.V.
Netherlands · score 0.0
1% 1.9 bn — — -0.2 bn -9.0% — Oral medicines for hereditary angioedema, from the Netherlands · Netherlands
25 MLYS Mineralys Therapeutics, Inc.
United States · score 0.0
1% 1.8 bn — — -0.1 bn -7.5% — Biopharma for aldosterone-driven diseases · Pennsylvania
26 PVLA PALVELLA THERAPEUTICS, INC.
United States · score 0.4
1% 1.8 bn — — -0.0 bn -2.1% — Drugs for rare cutaneous vascular malformations · Pennsylvania
27 BRVE Braveheart Bio, Inc.
United States · score 4.0
1% 1.7 bn — — — — — — Cardiovascular biotech · California
28 BHVN Biohaven Ltd.
United States · score 0.0
1% 1.7 bn — — -0.5 bn -29.9% — Biopharma in immunology, neuroscience and oncology · Connecticut
29 TRVI Trevi Therapeutics, Inc.
United States · score 0.1
1% 1.7 bn — — -0.1 bn -3.1% — Clinical-stage biopharma of a treatment for chronic cough · Connecticut
30 MAZE Maze Therapeutics, Inc.
United States · score 0.1
1% 1.6 bn 0.0 bn -53x -0.1 bn -6.5% — Clinical-stage biopharma of precision medicine for kidney and metabolic diseases · California — revenue of $2m
31 GPCR Structure Therapeutics Inc.
United States · score 0.0
1% 1.6 bn — — -0.2 bn -14.3% — Clinical-stage biopharma of oral molecules for chronic diseases · California
32 CMPS COMPASS Pathways plc
United Kingdom · score 0.0
1% 1.5 bn — — -0.2 bn -10.5% — Evidence-based innovation biotech for mental health · United Kingdom
33 KLRA Kailera Therapeutics, Inc.
United States · score 5.0
1% 1.5 bn — — — — — — Obesity drugs licensed from Hengrui · Massachusetts
34 RAPP Rapport Therapeutics, Inc.
United States · score 0.0
1% 1.4 bn 0.0 bn -685.8% -0.1 bn -7.1% — Precision molecules for neurological and psychiatric disorders · Massachusetts — revenue of $20m
35 TYRA Tyra Biosciences, Inc.
United States · score 0.0
1% 1.3 bn — — -0.1 bn -8.3% — FGFR-targeted precision medicine in oncology · California
36 ORIC Oric Pharmaceuticals, Inc.
United States · score 0.0
1% 1.3 bn — — -0.1 bn -8.5% — Clinical-stage biopharma in cancer resistance · California
37 LBRX LB PHARMACEUTICALS INC
United States · score 0.4
1% 1.3 bn — — -0.1 bn -6.6% — Therapies for schizophrenia and bipolar depression · New York
38 KARD Kardigan, Inc.
United States · score 5.0
1% 1.2 bn — — — — — — Cardiovascular medicines backed by digital patient data · California
39 GHRS GH Research PLC
Ireland · score 0.4
1% 1.1 bn — — -0.1 bn -4.6% — Clinical-stage biopharma of a depression treatment · Ireland
40 NBTX Nanobiotix S.A.
France · score 0.0
1% 1.0 bn 0.0 bn -42.6% -0.0 bn -3.9% — Nanoparticle-enhanced radiotherapy, from France · France — revenue of $13m
41 AVLN Avalyn Pharma Inc.
United States · score 5.2
1% 1.0 bn — — — — — — Inhaled medicines for pulmonary fibrosis · Massachusetts
42 SPTX Seaport Therapeutics, Inc.
United States · score 5.0
1% 1.0 bn — — — — — — Neuropsychiatry medicines · Massachusetts
43 GLUE Monte Rosa Therapeutics, Inc.
United States · score 0.0
0% 0.9 bn 0.0 bn -560.8% -0.0 bn -3.5% — Clinical-stage biotech of molecular glue degraders · Massachusetts — revenue of $29m
44 LTGO Latigo Biotherapeutics, Inc.
United States · score 4.0
1% 0.9 bn — — — — — — Clinical-stage non-opioid pain medicines · California
45 ANRO Alto Neuroscience, Inc.
United States · score 0.0
0% 0.9 bn — — -0.1 bn -7.7% — Clinical-stage precision psychiatry biopharma · California
46 AVBP ArriVent BioPharma, Inc.
United States · score 0.0
0% 0.9 bn — — -0.1 bn -16.7% — Clinical-stage biopharma in oncology drugs · Pennsylvania
47 AKTS Aktis Oncology, Inc.
United States · score 0.0
0% 0.8 bn 0.0 bn -727.0% -0.1 bn — -10.1% — Targeted radiopharmaceuticals for solid tumors · Massachusetts — revenue of $10m
48 ALMS ALUMIS INC.
United States · score 0.0
0% 0.8 bn 0.0 bn -59x -0.3 bn -42.9% — Clinical-stage biopharma in TYK2 inhibitors · California — revenue of $7m
49 SGP SpyGlass Pharma, Inc.
United States · score 0.4
0% 0.8 bn — — -0.1 bn -6.0% — Late-stage biopharma of sustained-release eye treatments · California
50 CRVS Corvus Pharmaceuticals, Inc.
United States · score 0.0
0% 0.8 bn — — -0.1 bn -5.6% — Clinical-stage biopharma of immune system proteins · California
51 HELP CYBIN INC.
Canada · score 0.0
0% 0.8 bn — — -0.1 bn -17.1% — Psychedelics for mental health, from Canada · Canada
52 LXRX LEXICON PHARMACEUTICALS, INC.
United States · score 0.0
0% 0.7 bn 0.0 bn -147.4% -0.1 bn -9.4% — Biopharma developing transformative medicines · Texas — revenue of $41m
53 ANL Adlai Nortye Group Ltd.
Singapore · score 0.0
0% 0.7 bn 0.0 bn -710.6% -0.0 bn -5.0% — Clinical-stage oncology, from China · Singapore — revenue of $5m
54 IVA Inventiva S.A.
France · score 0.0
0% 0.7 bn 0.0 bn -5051x -0.1 bn -15.4% — Medicines for liver diseases, from France · France
55 DSGN Design Therapeutics, Inc.
United States · score 0.0
0% 0.7 bn 0.0 bn — -0.1 bn -8.3% — GeneTAC molecules for genetic diseases · California
56 ACHV ACHIEVE LIFE SCIENCES, INC.
United States · score 0.0
0% 0.7 bn — — -0.1 bn -6.9% — Medicines for nicotine dependence · Washington
57 SGMT Sagimet Biosciences Inc.
United States · score 0.0
0% 0.6 bn — — -0.0 bn -6.7% — Clinical-stage biopharma in FASN inhibitors · California
58 OLMA Olema Pharmaceuticals, Inc.
United States · score 0.0
0% 0.6 bn — — -0.2 bn -26.5% — Clinical-stage biopharma in breast cancer therapies · California
59 NVCT Nuvectis Pharma, Inc.
United States · score 0.0
0% 0.6 bn — — -0.0 bn -3.2% — Clinical-stage biopharma in precision oncology medicine · New Jersey
60 DBVT DBV Technologies S.A.
France · score 0.0
0% 0.5 bn 0.0 bn -35x -0.2 bn -32.1% — Late-stage immunotherapy biopharma with the Viaskin platform · France — revenue of $5m
61 ACRS Aclaris Therapeutics, Inc.
United States · score 0.0
0% 0.5 bn 0.0 bn -921.5% -0.1 bn -12.1% — Immuno-inflammatory drugs in development and partnerships · Pennsylvania — revenue of $8m
62 ENTX Entera Bio Ltd.
Israel · score 0.2
0% 0.5 bn 0.0 bn — -0.0 bn -2.2% — Clinical-stage oral formulations of peptides and proteins · Israel
63 MNPR Monopar Therapeutics
United States · score 0.3
0% 0.5 bn 0.0 bn — -0.0 bn -2.5% — Clinical-stage cancer medicines · Illinois
64 DRUG BRIGHT MINDS BIOSCIENCES INC.
United States · score 0.4
0% 0.5 bn — — -0.0 bn -1.2% — Next-generation psychedelics for neuropsychiatric disorders · Illinois
65 FTH Faeth Therapeutics, Inc.
United States · score 0.0
0% 0.5 bn — — -0.0 bn -6.7% — Clinical-stage biotech inhibiting oncogenic pathways · Texas
66 BLSM BlossomHill Therapeutics, Inc.
United States · score 4.0
0% 0.5 bn — — — — — — Small-molecule drugs for EGFR-mutant lung cancer and acute myeloid leukemia, in clinical stage · California
67 CCCC C4 Therapeutics, Inc.
United States · score 0.0
0% 0.4 bn 0.0 bn -289.4% -0.1 bn -24.0% — Clinical-stage biopharma of targeted protein degradation · Massachusetts — revenue of $35m
68 ALT Altimmune, Inc.
United States · score 0.0
0% 0.4 bn 0.0 bn -2238x -0.1 bn -17.6% — Drugs for serious liver diseases · Maryland
69 OCS Oculis Holding AG
Switzerland · score 0.0
0% 0.4 bn 0.0 bn -68x -0.1 bn -18.8% — Ophthalmic therapies, from Switzerland · Switzerland — revenue of $1m
70 OVID Ovid Therapeutics Inc.
United States · score 0.0
0% 0.4 bn 0.0 bn -22x -0.1 bn -12.9% — Biopharma in small molecules for brain disorders · New York — revenue of $2m
71 GALT GALECTIN THERAPEUTICS INC
United States · score 0.0
0% 0.4 bn — — -0.0 bn -4.5% — Clinical-stage biopharma in fibrosis and cancer · Georgia
72 AVIR Atea Pharmaceuticals, Inc.
United States · score 0.0
0% 0.4 bn — — -0.1 bn -43.2% — Late-stage biopharma in oral antivirals · Massachusetts
73 PRLD Prelude Therapeutics Inc
United States · score 0.0
0% 0.3 bn 0.0 bn -269.7% -0.0 bn -12.3% — Clinical-stage precision oncology · Delaware — revenue of $22m
74 XFOR X4 Pharmaceuticals, Inc
United States · score 0.0
0% 0.3 bn 0.0 bn -10x -0.1 bn -30.7% — Biopharma in rare blood disorders · Massachusetts — revenue of $9m
75 FULC Fulcrum Therapeutics, Inc.
United States · score 0.0
0% 0.3 bn 0.0 bn — -0.1 bn -23.4% — Clinical-stage biopharma in rare genetic diseases · Massachusetts
76 RLMD RELMADA THERAPEUTICS, INC.
United States · score 0.0
0% 0.3 bn — — -0.1 bn -13.6% — Clinical-stage biotech · Florida
77 TTRX Turn Therapeutics Inc.
United States · score 0.2
0% 0.3 bn — — 0.0 bn -1.4% — Clinical-stage topical antimicrobials · California
78 CTNM Contineum Therapeutics, Inc.
United States · score 0.0
0% 0.3 bn — — -0.1 bn -19.1% — Clinical-stage biopharma in neuroimmune diseases · California
79 ACIU AC Immune SA
Switzerland · score 0.0
0% 0.2 bn 0.0 bn -246.5% -0.1 bn -25.0% — Therapies for Alzheimer's and neurodegenerative diseases, from Switzerland · Switzerland — revenue of $21m
80 ACOG Alpha Cognition Inc.
United States · score 0.0
0% 0.2 bn 0.0 bn -137.7% -0.0 bn -16.8% — Biopharma for neurodegenerative diseases such as Alzheimer's · Texas — revenue of $15m
81 BIOA BioAge Labs, Inc.
United States · score 0.0
0% 0.2 bn 0.0 bn -912.3% -0.1 bn -38.5% — Clinical-stage biopharma in metabolic diseases of aging · California — revenue of $10m
82 EVMN Evommune, Inc.
United States · score 0.0
0% 0.2 bn 0.0 bn -946.7% -0.1 bn -39.0% — Therapies for chronic inflammatory diseases · California — revenue of $10m
83 PALI PALISADE BIO, INC.
United States · score 0.0
0% 0.2 bn 0.0 bn — -0.0 bn -7.8% — Clinical-stage biopharma of oral PDE4 inhibitors · California
84 IKT Inhibikase Therapeutics, Inc.
United States · score 0.0
0% 0.2 bn 0.0 bn — -0.0 bn -18.6% — Clinical-stage pharma in pulmonary arterial hypertension · Delaware
85 ZNTL Zentalis Pharmaceuticals, Inc.
United States · score 0.0
0% 0.2 bn 0.0 bn — -0.1 bn -57.8% — Clinical-stage biopharma with a WEE1 inhibitor · California
86 IFRX InflaRx N.V.
Germany · score 0.0
0% 0.2 bn 0.0 bn -1551x -0.0 bn -18.5% — Complement system inhibitors (C5a/C5aR) for inflammatory and autoimmune diseases, in clinical development · Germany
87 SLGL Sol-Gel Technologies Ltd.
Israel · score 0.1
0% 0.2 bn 0.0 bn -910.1% -0.0 bn -4.0% — Topical dermatology, from Israel · Israel — revenue of $2m
88 ORMP ORAMED PHARMACEUTICALS INC.
United States · score 2.7
0% 0.2 bn 0.0 bn 87x -0.0 bn -3.1% — Oral delivery of therapeutic proteins, from Israel · New York — revenue of $2m
89 CATX Perspective Therapeutics, Inc.
United States · score 0.0
0% 0.2 bn — — -0.1 bn -48.5% — Radiopharmaceuticals for cancer treatment · Washington
90 IMRX Immuneering Corp
United States · score 0.0
0% 0.2 bn — — -0.1 bn -24.1% — Late clinical-stage oncology · Massachusetts
91 VOGX Vogenx, Inc.
United States · score 4.0
0% 0.2 bn — — — — — — Oral drug for post-bariatric surgery hypoglycemia and gastroparesis, in clinical development · North Carolina
92 BBOT BridgeBio Oncology Therapeutics, Inc.
United States · score 0.0
0% 0.2 bn — — -0.1 bn -66.3% — Oncology targeting RAS and PI3Kα mutations · California
93 SION Sionna Therapeutics, Inc.
United States · score 0.0
0% 0.2 bn — — -0.1 bn -42.0% — Clinical-stage biopharma in cystic fibrosis · Massachusetts
94 SPRO Spero Therapeutics, Inc.
United States · score 7.4
0% 0.1 bn 0.1 bn 15.7% 0.0 bn 30.0% — Clinical-stage biopharma in rare diseases · Massachusetts — revenue of $47m
95 FHTX Foghorn Therapeutics Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn -175.8% -0.1 bn -75.9% — Clinical-stage biotech in chromatin regulation · Massachusetts — revenue of $37m
96 VTVT vTv Therapeutics Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn -12.9% -0.0 bn -15.7% — Late-stage biopharma in metabolic and inflammatory diseases · North Carolina — revenue of $37m
97 CPIX CUMBERLAND PHARMACEUTICALS INC
United States · score 2.5
0% 0.1 bn 0.0 bn -27.4% 0.0 bn 0.7% — Specialty pharma of branded prescription drugs · Tennessee — revenue of $40m
98 PTHS Pelthos Therapeutics Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn -199.5% -0.0 bn -54.9% — Biopharma developing innovative therapeutics · North Carolina — revenue of $43m
99 TNXP Tonix Pharmaceuticals Holding Corp.
United States · score 0.0
0% 0.1 bn 0.0 bn -548.6% -0.2 bn -160.8% — Drug for fibromyalgia and other nervous system conditions · New Jersey — revenue of $29m
100 VRCA Verrica Pharmaceuticals Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn -102.8% -0.0 bn -22.6% — Therapies for skin diseases, including skin cancer · Pennsylvania — revenue of $30m
101 LENZ LENZ Therapeutics, Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn -586.7% -0.1 bn -110.3% — Commercial pharma of vision therapies · California — revenue of $21m
102 SPRB SPRUCE BIOSCIENCES, INC.
United States · score 0.0
0% 0.1 bn 0.0 bn — -0.0 bn -36.7% — Biopharma in therapies for neurological disorders · California
103 NRXP NRX Pharmaceuticals, Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn -691.8% -0.0 bn -17.4% — Interventional psychiatry and neuroplastic therapies · Delaware — revenue of $3m
104 BDTX Black Diamond Therapeutics, Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn — -0.0 bn -31.6% — Clinical-stage oncology of therapies for oncogenic mutations · Massachusetts
105 MBRX Moleculin Biotech, Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn — -0.0 bn -24.7% — Biopharma of a next-generation anthracycline · Texas
106 VANI Vivani Medical, Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn — -0.0 bn -26.2% — Clinical-stage biopharma of sustained-release implants · California
107 RANI Rani Therapeutics Holdings, Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn -618.0% -0.0 bn -22.4% — Clinical-stage biotech of oral delivery of biologics · California — revenue of $5m
108 AARD Aardvark Therapeutics, Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn — -0.1 bn -84.9% — Molecules for metabolic diseases and obesity · California
109 NTRB NutriBand Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn -430.3% 0.0 bn -5.0% — Transdermal patches for drug delivery · Florida — revenue of $2m
110 CRDF Cardiff Oncology, Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn -79x -0.0 bn -59.1% — Clinical-stage biotech in PLK1 inhibition for oncology · California
111 MNOV MEDICINOVA INC
United States · score 0.0
0% 0.1 bn 0.0 bn -12x -0.0 bn -13.2% — Biopharma of therapies for serious diseases · California
112 RFL Rafael Holdings, Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn -21x -0.0 bn -47.7% — Biotech and stakes in pharmaceutical companies · New Jersey
113 TENX TENAX THERAPEUTICS, INC.
United States · score 0.0
0% 0.1 bn 0.0 bn — -0.1 bn -80.9% — Clinical-stage cardiovascular drugs · North Carolina
114 TLPH TALPHERA, INC.
United States · score 0.0
0% 0.1 bn 0.0 bn -15076x -0.0 bn -21.9% — Specialty pharma for medically supervised use · California
115 PLRX PLIANT THERAPEUTICS, INC.
United States · score 0.0
0% 0.1 bn 0.0 bn — -0.1 bn -127.3% — Integrin-based therapies for fibrosis · California
116 ELOX Eloxx Pharmaceuticals, Inc.
United States · score 0.0
0% 0.1 bn 0.0 bn — -0.0 bn -31.7% — Premature stop codon readthrough molecules · Massachusetts
117 MENS Jyong Biotech Ltd.
Taiwan · score 0.0
0% 0.1 bn — — 0.0 bn -2.1% — Botanical medicines, from Taiwan, since 2002 · Taiwan
118 ANTX AN2 Therapeutics, Inc.
United States · score 0.0
0% 0.1 bn — — -0.0 bn -24.1% — Clinical-stage biopharma in boron chemistry · California
119 AVXL ANAVEX LIFE SCIENCES CORP.
United States · score 0.0
0% 0.1 bn — — -0.0 bn -25.3% — Medicines for Alzheimer's, Parkinson's and rare diseases · New York
120 NERV Minerva Neurosciences, Inc.
United States · score 0.6
0% 0.1 bn — — -0.0 bn -23.6% — Medicines for central nervous system diseases · Massachusetts
121 UNCY Unicycive Therapeutics, Inc.
United States · score 0.0
0% 0.1 bn — — -0.0 bn -28.5% — Clinical-stage biotech in kidney disease · California
122 PLYX Polaryx Therapeutics, Inc.
United States · score 0.5
0% 0.1 bn — — -0.0 bn -6.1% — Clinical-stage biotech in pediatric lysosomal diseases · New Jersey
123 IMUX IMMUNIC, INC.
United States · score 0.0
0% 0.1 bn — — -0.1 bn -92.3% — Late-stage biotech of oral therapies for neurological and gastrointestinal diseases · United States
124 PMVP PMV Pharmaceuticals, Inc.
United States · score 0.0
0% 0.1 bn — — -0.1 bn -75.2% — Precision oncology targeting the p53 protein · New Jersey
125 OKUR OnKure Therapeutics, Inc.
United States · score 0.0
0% 0.1 bn — — -0.1 bn -52.5% — Clinical-stage biopharma in precision oncology medicine · Colorado
126 NMRA Neumora Therapeutics, Inc.
United States · score 0.0
0% 0.1 bn — — -0.2 bn -204.4% — Clinical-stage biopharma of brain-penetrant chemistry · Massachusetts
127 MIST Milestone Pharmaceuticals Inc.
Canada · score 0.0
0% 0.1 bn — — -0.1 bn -70.8% — Pharma of the CARDAMYST nasal spray · Canada
128 OKYO OKYO Pharma Ltd
United Kingdom · score 0.0
0% 0.1 bn — — -0.0 bn -8.1% — Ophthalmic therapies for neuropathic eye pain · United Kingdom
129 ACRV Acrivon Therapeutics, Inc.
United States · score 0.0
0% 0.1 bn — — -0.1 bn -88.6% — Clinical-stage biopharma in precision proteomics · Massachusetts
130 TELO Telomir Pharmaceuticals, Inc.
United States · score 0.0
0% 0.1 bn — — 0.0 bn -6.9% — Preclinical biotech of anti-aging molecules · Florida
131 CGTX COGNITION THERAPEUTICS INC
United States · score 0.0
0% 0.1 bn — — -0.0 bn -25.6% — Clinical-stage biopharma for degenerative CNS diseases · New York
132 MAIA MAIA Biotechnology, Inc.
United States · score 0.0
0% 0.1 bn — — -0.0 bn -34.7% — Clinical-stage biopharma in cancer immunotherapies · Illinois
133 CING Cingulate Inc.
United States · score 0.0
0% 0.1 bn — — -0.0 bn -33.0% — Pharma developing timed-release drug delivery · Kansas
134 BMEA Biomea Fusion, Inc.
United States · score 0.0
0% 0.1 bn — — -0.1 bn -78.0% — Clinical-stage biopharma in diabetes and obesity · California
135 GANX Gain Therapeutics, Inc.
United States · score 0.0
0% 0.1 bn — — -0.0 bn -34.7% — Biotech in small molecules for CNS and lysosomal diseases · Maryland
136 BOLD Boundless Bio, Inc.
United States · score 0.0
0% 0.1 bn — — -0.1 bn -108.1% — Oncology targeting extrachromosomal DNA · California
137 BFRI Biofrontera Inc.
United States · score 0.0
0% 0.0 bn 0.1 bn -13.8% -0.0 bn -66.1% — Biopharma in photodynamic therapy for dermatology · Massachusetts — revenue of $46m
138 SCLX Scilex Holding Co
United States · score 0.0
0% 0.0 bn 0.0 bn -15x -0.0 bn -81.7% — Non-opioid pain management products · California — revenue of $32m
139 SCYX SCYNEXIS INC
United States · score 0.0
0% 0.0 bn 0.0 bn -53.3% -0.0 bn -36.6% — Antifungal for resistant infections · New Jersey — revenue of $19m
140 ATHE ALTERITY THERAPEUTICS LTD
Australia · score 0.0
0% 0.0 bn 0.0 bn -289.3% -0.0 bn -35.8% — Oral drug for multiple system atrophy and other Parkinsonian disorders, in clinical development · Australia — revenue of $6m
141 CTXR Citius Pharmaceuticals, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -818.7% -0.0 bn -298.0% — Biopharma in critical care and oncology products · New Jersey — revenue of $7m
142 PTN PALATIN TECHNOLOGIES INC
United States · score 0.0
0% 0.0 bn 0.0 bn -94.9% -0.0 bn -127.0% — Biopharma of melanocortin system modulators · New Jersey — revenue of $9m
143 RNTX Rein Therapeutics, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn — -0.0 bn -39.6% — Therapies for pulmonary fibrosis and rare diseases · Texas
144 CLNN Clene Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -201x -0.0 bn -37.7% — Clinical-stage pharma in clean-surface nanotechnology · Utah
145 SER Serina Therapeutics, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn — -0.0 bn -50.6% — Clinical-stage biotech in neurological diseases · Alabama
146 ATNM Actinium Pharmaceuticals, Inc.
United States · score 1.1
0% 0.0 bn 0.0 bn 126x -0.0 bn -54.9% — Radiopharmaceuticals for solid tumors and blood cancers · New York
147 ANVS Annovis Bio, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn — -0.0 bn -106.0% — Late-stage pharma in Alzheimer's and Parkinson's · Pennsylvania
148 EYPT EyePoint, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -110x -0.3 bn -715.8% — Clinical-stage biopharma in serious retinal diseases · Massachusetts — revenue of $3m
149 CRVO CervoMed Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -92x -0.0 bn -80.2% — Clinical-stage biotech in brain disorders of aging · Massachusetts
150 IXHL Incannex Healthcare Inc.
Australia · score 0.0
0% 0.0 bn 0.0 bn — -0.0 bn -37.2% — Clinical-stage biopharma in serious chronic diseases · Australia
151 NNVC NANOVIRICIDES, INC.
United States · score 0.0
0% 0.0 bn 0.0 bn — -0.0 bn -23.4% — Clinical-stage biotech with its first drug in phase II · Connecticut
152 CPHI CHINA PHARMA HOLDINGS, INC.
China · score 0.6
0% 0.0 bn 0.0 bn -114.3% 0.0 bn -0.7% — Pharmaceutical holding company in China · China — revenue of $4m
153 IBO IMPACT BIOMEDICAL INC.
United States · score 1.6
0% 0.0 bn 0.0 bn 23x 0.0 bn -1.9% — Discovery and patenting of biomedical science to license to health and wellness partners · Texas
154 IGC IGC Pharma, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -702.1% -0.0 bn -23.9% — Alzheimer's therapies using cannabinoids and AI · Maryland — revenue of $1m
155 ABVC ABVC BIOPHARMA, INC.
United States · score 0.0
0% 0.0 bn 0.0 bn -890.6% 0.0 bn -11.1% — Seven licensed drugs and one medical device in development · California
156 BYSI BeyondSpring Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn — -0.0 bn -79.4% — Global clinical-stage biopharma in oncology · New Jersey
157 NEUP Neuphoria Therapeutics Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -11x -0.0 bn -69.0% — Clinical-stage biotech in neuropsychiatric disorders · Massachusetts — revenue of $1m
158 DARE Dare Bioscience, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -804.3% -0.0 bn -84.6% — Biotech focused on women's health · California — revenue of $1m
159 ALLR Allarity Therapeutics, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -36x -0.0 bn -99.2% — Pharma in precision oncology medicine · Massachusetts
160 HIND Vyome Holdings, Inc
United States · score 0.0
0% 0.0 bn 0.0 bn -87x -0.0 bn -43.2% — Next-generation antibiotics in partnership with Sun Pharma · California
161 LPCN Lipocine Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -755.3% -0.0 bn -88.8% — Oral delivery of poorly absorbed molecules · United States — revenue of $2m
162 ASBP Aspire Biopharma Holdings, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -1842x -0.0 bn -60.9% — Sublingual delivery of known drugs and supplements, such as aspirin and caffeine, at an early stage · Florida
163 KPRX KIORA PHARMACEUTICALS INC
United States · score 0.0
0% 0.0 bn 0.0 bn — -0.0 bn -82.0% — Clinical-stage pharma in retinal diseases · California
164 BLRX BioLineRx Ltd.
Israel · score 0.0
0% 0.0 bn 0.0 bn -728.4% -0.0 bn -109.4% — Therapies for oncology and rare diseases, from Israel · Israel — revenue of $1m
165 ENSC Ensysce Biosciences, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -280.5% -0.0 bn -91.6% — Clinical-stage pharma in pain relief with lower abuse risk · California — revenue of $5m
166 VTGN Vistagen Therapeutics, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -27x -0.1 bn -700.0% — Late-stage therapies for social anxiety, depression and hot flashes · California — revenue of $3m
167 INM InMed Pharmaceuticals Inc.
Canada · score 0.0
0% 0.0 bn 0.0 bn -278.7% -0.0 bn -115.3% — Development of molecules for cannabinoid receptors · Canada — revenue of $5m
168 XCUR EXICURE, INC.
United States · score 0.0
0% 0.0 bn 0.0 bn — -0.0 bn -95.3% — Burixafor, a CXCR4 inhibitor for acute myeloid leukemia; exploring strategic alternatives · Illinois
169 TRAW Traws Pharma, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -773.0% -0.0 bn -340.9% — Clinical-stage biopharma in respiratory viral diseases · Pennsylvania — revenue of $3m
170 CANF Can-Fite BioPharma Ltd.
Israel · score 0.0
0% 0.0 bn 0.0 bn -24x -0.0 bn -166.9% — Oral molecules for cancer and liver diseases, from Israel · Israel
171 ADXN Addex Therapeutics Ltd.
Switzerland · score 0.0
0% 0.0 bn 0.0 bn -83x 0.0 bn -58.0% — Allosteric modulators for neurological diseases, from Switzerland · Switzerland
172 SCNX Scienture Holdings, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -46x -0.0 bn -300.9% — Cardiovascular and neurological specialty pharma · New York
173 XTLB XTL BIOPHARMACEUTICALS LTD
Israel · score 0.4
0% 0.0 bn 0.0 bn — 0.0 bn -23.5% — Psychedelic medicines (psilocybin, ibogaine) for mental and neurological disorders, in clinical development · Israel
174 GELS Gelteq Ltd
Australia · score 0.0
0% 0.0 bn 0.0 bn -43x 0.0 bn -83.9% — Oral gels for delivering medicines and supplements, from Australia · Australia
175 RDHL RedHill Biopharma Ltd.
Israel · score 0.0
0% 0.0 bn 0.0 bn — -0.0 bn -204.7% — Specialty biopharma for gastroenterology and oncology · Israel
176 SXTP 60 DEGREES PHARMACEUTICALS, INC.
United States · score 0.0
0% 0.0 bn 0.0 bn -729.9% -0.0 bn -306.7% — Drugs for tropical and infectious diseases · Washington, DC — revenue of $1m
177 PRFX PRF Technologies Ltd.
Israel · score 0.0
0% 0.0 bn 0.0 bn -182x 0.0 bn -176.4% — Reformulation of established medicines · Israel
178 NXTS Nexentis Technologies Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -77x 0.0 bn -493.7% — Solar projects and oncology biotech · New York
179 CRIS CURIS INC
United States · score 0.0
0% 0.0 bn 0.0 bn -490.3% -0.0 bn -38x — Biotech developing an IRAK4 and FLT3 inhibitor · Massachusetts — revenue of $4m
180 LONA LeonaBio, Inc.
United States · score 0.0
0% 0.0 bn — — -0.1 bn -130.1% — Clinical-stage biopharma for breast cancer and ALS · Washington
181 DWTX Dogwood Therapeutics, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -36.8% — Pre-revenue biopharma in pain and neuropathy drugs · Georgia
182 ALDX Aldeyra Therapeutics, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -54.9% — Biotech in therapies for immune-mediated diseases · Massachusetts
183 GRCE Grace Therapeutics, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -26.0% — Rare disease drugs with novel routes of administration · New Jersey
184 VERU VERU INC.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -66.1% — Late clinical-stage biopharma in cardiometabolic diseases · Florida
185 QNCX Quince Therapeutics, Inc.
United States · score 0.0
0% 0.0 bn — — -0.1 bn -134.3% — Biotech developing therapies for rare diseases · California
186 FLNA FILANA THERAPEUTICS, INC.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -89.3% — Development of drugs for nervous system disorders · Texas
187 MIRA MIRA PHARMACEUTICALS, INC.
United States · score 0.0
0% 0.0 bn — — 0.0 bn -17.2% — Oral drugs for neurological and metabolic diseases · Florida
188 ATOS ATOSSA THERAPEUTICS, INC.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -140.3% — Oncology drugs, focused on breast cancer · Washington
189 SHPH Shuttle Pharmaceuticals Holdings, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -29.3% — Radiosensitizers for cancer treatment · Maryland
190 QNRX Quoin Pharmaceuticals Ltd.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -80.0% — Late-stage pharma in rare and orphan diseases · Virginia
191 COCP Cocrystal Pharma, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -43.5% — Clinical-stage biotech in antivirals · Washington
192 ACTU ACTUATE THERAPEUTICS, INC.
United States · score 1.2
0% 0.0 bn — — -0.0 bn -137.7% — Elraglusib, a GSK-3β inhibitor for cancer · Texas
193 KTTA Pasithea Therapeutics Corp.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -128.9% — Clinical-stage biotech in RASopathies and MAPK pathway tumors · Florida
194 REVB REVELATION BIOSCIENCES, INC.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -71.2% — Clinical-stage life sciences in rebalancing inflammation · California
195 TVRD Tvardi Therapeutics, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -194.0% — Clinical-stage biopharma in oral STAT3 inhibitors · Texas
196 INTS INTENSITY THERAPEUTICS, INC.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -83.7% — Late-stage biotech in localized tumor reduction · Connecticut
197 CLRB Cellectar Biosciences, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -183.8% — Late-stage biopharma in cancer treatments · New Jersey
198 TPST Tempest Therapeutics, Inc.
United States · score 0.2
0% 0.0 bn — — -0.0 bn -205.2% — Clinical-stage biotech in cell therapy and small molecules · California
199 ADIL ADIAL PHARMACEUTICALS, INC.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -117.2% — Clinical-stage biopharma of addiction treatments · Virginia
200 MTVA MetaVia Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -195.5% — Clinical-stage biotech in cardiometabolic diseases · Massachusetts
201 CURX Curanex Pharmaceuticals Inc
United States · score 0.0
0% 0.0 bn — — -0.0 bn -156.9% — Plant-derived oral medicine for respiratory diseases · New York
202 SNGX SOLIGENIX, INC.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -131.7% — Specialty biotech and public health solutions · New Jersey
203 CNSP CNS Pharmaceuticals, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -184.1% — Biotech in neurology and oncology therapies · Texas
204 CALC CalciMedica, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -273.1% — Clinical-stage biopharma in inflammatory and immune diseases · California
205 APRE Aprea Therapeutics, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -181.6% — Clinical-stage precision oncology for biomarker-defined cancers · Pennsylvania
206 ALZN Alzamend Neuro, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -106.9% — Drugs for Alzheimer's and bipolar disorder · Georgia
207 ENVB Enveric Biosciences, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -138.1% — Biotech of neuroplastogens for psychiatric disorders · Massachusetts
208 ACXP Acurx Pharmaceuticals, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -103.0% — Late-stage biopharma in antibiotics for hard-to-treat infections · New York
209 PULM Pulmatrix, Inc.
United States · score 0.0
0% 0.0 bn — — 0.0 bn -75.2% — Biopharma in inhaled therapies for migraine and respiratory disease · Massachusetts
210 PCSA Processa Pharmaceuticals, Inc.
United States · score 0.2
0% 0.0 bn — — -0.0 bn -249.4% — Clinical-stage biopharma · Florida
211 NCNA NuCana plc
United Kingdom · score 0.0
0% 0.0 bn — — -0.0 bn -166.6% — ProTide chemotherapy drugs (modified nucleoside analogs) for cancer, in clinical development · United Kingdom
212 CVKD Cadrenal Therapeutics, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -267.6% — Late-stage biopharma in immune and thrombotic diseases · Florida
213 GRI GRI Bio, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -325.6% — Clinical-stage biopharma in inflammatory and autoimmune diseases · California
214 EOCN Galmed Pharmaceuticals Ltd.
Israel · score 0.0
0% 0.0 bn — — -0.0 bn -284.8% — Medicines for liver diseases, from Israel · Israel
215 OGEN ORAGENICS INC
United States · score 0.0
0% 0.0 bn — — -0.0 bn -537.2% — Nasally administered medicines for neurological diseases · Florida
216 MTNB Matinas BioPharma Holdings, Inc.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -401.3% — Clinical-stage biopharma of lipid nanocrystals · New Jersey
217 ARTL ARTELO BIOSCIENCES, INC.
United States · score 0.0
0% 0.0 bn — — -0.0 bn -902.4% — Clinical-stage biopharma in the endocannabinoid system · California
218 LABT Lakewood-Amedex Biotherapeutics Inc.
United States · score 0.0
0% 0.0 bn — — 0.0 bn -249.0% — Biotech for infectious diseases · Florida
219 BGM BGM Group Ltd.
China · score 1.5
— — 0.0 bn -52.6% 0.0 bn — — Pharmaceutical holding company operating in China · China — revenue of $38m
220 JAGX Jaguar Health, Inc.
United States · score 0.3
— — 0.0 bn -192.6% -0.0 bn — — Plant-derived drugs for gastrointestinal diseases · California — revenue of $28m
221 APLM Apollomics Inc.
United States · score 0.0
— — 0.0 bn -128.7% -0.0 bn — — Cancer drugs, including a c-Met inhibitor for lung cancer, in clinical stage · California — revenue of $8m
222 RADX Radiopharm Theranostics Ltd
Australia · score 0.3
— — 0.0 bn -21x -0.1 bn — — Radiopharmaceuticals for diagnosis and therapy, from Australia · Australia — revenue of $3m
223 SXTC China SXT Pharmaceuticals, Inc.
China · score 1.1
— — 0.0 bn -545.3% 0.0 bn — — Traditional Chinese medicine in tablets and powder · China — revenue of $1m
224 SPRC SciSparc Ltd.
Israel · score 0.8
— — 0.0 bn -14x -0.0 bn — — Medicines for central nervous system disorders, from Israel · Israel
225 LEXX Lexaria Bioscience Corp.
Canada · score 0.4
— — 0.0 bn -40x -0.0 bn — — Bioavailability biotech with DehydraTECH technology · Canada
226 LSTA LISATA THERAPEUTICS, INC.
United States · score 0.4
— — 0.0 bn -146x -0.0 bn — — Clinical-stage pharma in solid tumors · New Jersey
227 SILO Silo Pharma, Inc.
United States · score 0.6
— — 0.0 bn -83x 0.0 bn — — Biopharma in development and digital assets · Florida
228 KZIA KAZIA THERAPEUTICS LTD
Australia · score 0.8
— — 0.0 bn -549x -0.0 bn — — Clinical-stage oncology, from Australia · Australia
229 JUNS JUPITER NEUROSCIENCES, INC.
United States · score 0.0
— — 0.0 bn -418x -0.0 bn — — Clinical-stage neuroinflammation research on a resveratrol platform · Florida
230 TCRT Alaunos Therapeutics, Inc.
United States · score 0.4
— — 0.0 bn -1337x 0.0 bn — — Preclinical biopharma in obesity and metabolic disorders · Florida
231 EPRX EUPRAXIA PHARMACEUTICALS INC.
Canada · score 1.2
— — 0.0 bn — -0.0 bn — — Long-acting injectable medicines, from Canada · Canada
232 NTHI NEONC TECHNOLOGIES HOLDINGS, INC.
United States · score 2.3
— — 0.0 bn — -0.0 bn — — Drug delivery to the brain for brain tumors · California
233 MPLT MapLight Therapeutics, Inc.
United States · score 1.2
— — — — -0.2 bn — — Drugs for central nervous system disorders · California
234 CDT CDT Equity Inc.
United States · score 1.0
— — — — -0.0 bn — — Data-driven pharmaceutical development and digital asset treasury · Florida
235 UPC Universe Pharmaceuticals INC
China · score 3.0
— — — — -5.3 bn — — Traditional Chinese medicine in tablets and capsules · China
236 MSLE Satellos Bioscience Inc.
Canada · score 1.3
— — — — -0.0 bn — — Therapies for muscle regeneration, from Canada · Canada
237 MDCX Medicus Pharma Ltd.
United States · score 0.3
— — — — -0.0 bn — — Topical therapy for basal cell carcinoma · Pennsylvania
238 PPBT PURPLE BIOTECH LTD.
Israel · score 1.0
— — — — -0.0 bn — — Clinical-stage oncology drugs, from Israel · Israel
239 PBM PSYENCE BIOMEDICAL LTD.
Canada · score 1.4
— — — — -0.0 bn — — Natural psychedelics for mental health · Canada
240 BDRX Biodexa Pharmaceuticals Plc
United Kingdom · score 1.2
— — — — -0.0 bn — — Drugs for familial adenomatous polyposis, gastrointestinal cancer and type 1 diabetes, in clinical development · United Kingdom
241 CMND Clearmind Medicine Inc.
Canada · score 1.0
— — — — -0.0 bn — — Non-hallucinogenic psychedelic derivatives for alcohol use disorder and mental and metabolic disorders, in clinical development · Canada
242 CRDL Cardiol Therapeutics Inc.
Canada · score 0.8
— — — — -0.0 bn — — Clinical-stage cardiovascular therapies, from Canada · Canada
243 NGEN NERVGEN PHARMA CORP.
Canada · score 1.2
— — — — -0.0 bn — — Therapies for spinal cord injury, from Canada · Canada
244 PYPD PolyPid Ltd.
Israel · score 0.5
— — — — -0.0 bn — — Localized post-surgical drug delivery, from Israel · Israel
245 QNTM Quantum Biopharma Ltd.
Canada · score 3.6
— — — — -0.0 bn — — Licensed medicines for multiple sclerosis · Canada
246 BIVI BIOVIE INC.
United States · score 0.8
— — — — -0.0 bn — — Clinical-stage therapies for neurological disorders and liver disease · Nevada
247 NSRX Nasus Pharma Ltd
Israel · score 0.9
— — — — -0.0 bn — — Intranasal medicines for medical emergencies · Israel
248 DCOY Decoy Therapeutics Inc.
United States · score 0.8
— — — — -0.0 bn — — Preclinical biotech of peptide conjugates · Texas
249 DRMA Dermata Therapeutics, Inc.
United States · score 0.8
— — — — -0.0 bn — — Commercial dermatology for underserved skin conditions · California
250 XRTX XORTX Therapeutics Inc.
Canada · score 0.9
— — — — 0.0 bn — — Therapies for kidney diseases, from Canada · Canada
251 NRSN NeuroSense Therapeutics Ltd.
Israel · score 1.9
— — — — -0.0 bn — — PrimeC drug for amyotrophic lateral sclerosis, from Israel · Israel

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What this is. A catalogue, not a guide. Every industry with stocks listed on the NYSE or NASDAQ, the companies contending for its leadership, what each one does according to its own annual report, and the balance sheet it filed with the SEC.

The score runs from 0 to 10 and compares each company with every other one in the almanac on cash generation, profitability, debt, dividends and consistency over the last five years. The higher it is, the better the company fares in that comparison. Curious how much each part weighs? Ask at the bottom of the page.

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