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Genomics and sequencing

The 9 companies in this industry listed on the NYSE and Nasdaq are worth $69 bn combined; the largest are Illumina (ILMN), QIAGEN (QGEN) and 10x Genomics (TXG). For each one: what it does, revenue, margin, free cash flow over the last five years and a score from 0 to 10.

Data as of October 2026

Comfortable leader
9 companies value 69 bn revenue 7.9 bn margin 8.2% free cash flow 1.1 bn avg. score 1.7
ILMN holds 57.5% of the group's value, 3.9x the runner-up
Rank Ticker Company Share Value Revenue Margin FCF 5 years FCF/px Yield What it does · why it is here
1 ILMN Illumina
United States · score 5.8
57% 40 bn 4.5 bn 18.4% 0.9 bn 2.3% — Genomic sequencers and reagents · Dominates genetic sequencing (~80% of the world's genome data)
2 QGEN QIAGEN
Netherlands · score 6.1
15% 10 bn 2.1 bn 20.3% 0.5 bn 4.5% 0.5% Molecular diagnostic tests and supplies, from the Netherlands · Leader in sample preparation and molecular testing for labs
3 TXG 10x Genomics
United States · score 2.7
13% 9.1 bn 0.6 bn -12.2% 0.1 bn 1.3% — Single-cell and spatial genomics instruments · Leader in single-cell analysis, a technique that has become standard in research
4 TWST Twist Bioscience Corp
United States · score 0.1
13% 8.8 bn 0.4 bn -31.7% -0.1 bn -1.1% — Silicon-based DNA synthesis for research and biotech · California — revenue of $432m
5 PACB Pacific Biosciences
United States · score 0.0
1% 0.6 bn 0.2 bn -82.5% -0.1 bn -21.6% — Long-read DNA sequencers · Long-read sequencing, more accurate for complex genomes
6 SOPH SOPHiA GENETICS SA
Switzerland · score 0.0
1% 0.6 bn 0.1 bn -93.9% -0.0 bn -7.5% — Cloud-based genomic data analytics, from Switzerland · Switzerland — revenue of $86m
7 QSI Quantum-Si Inc
United States · score 0.0
0% 0.2 bn 0.0 bn -61x -0.1 bn -39.3% — Life sciences focused on single-molecule proteomics · Connecticut — revenue of $2m
8 BNGO Bionano Genomics, Inc.
United States · score 0.0
0% 0.0 bn 0.0 bn -106.6% -0.0 bn -142.2% — Genome analysis solutions for research and clinics · California — revenue of $30m
9 CODX Co-Diagnostics, Inc.
United States · score 0.6
— — 0.0 bn -65x -0.0 bn — — Reagents for molecular diagnostic tests for infectious diseases · Utah

Other industries in the same sector

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What this is. A catalogue, not a guide. Every industry with stocks listed on the NYSE or NASDAQ, the companies contending for its leadership, what each one does according to its own annual report, and the balance sheet it filed with the SEC.

The score runs from 0 to 10 and compares each company with every other one in the almanac on cash generation, profitability, debt, dividends and consistency over the last five years. The higher it is, the better the company fares in that comparison. Curious how much each part weighs? Ask at the bottom of the page.

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